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Handb Exp Pharmacol 196:369405 Holme JA, Hongslo JK, Bjrge C, Nelson SD (1991) Comparative cytotoxic effects of acetaminophen ( N -acetyl- p -aminophenol), a non-hepatotoxic regioisomer acetyl- m -aminophenol and their postulated reactive hydroquinone and quinone metabolites in monolayer cultures of mouse hepatocytes

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Moreover, after the activation of K-Ras and Akt in transformed cells, 60% of the total FADH 2 and NADH 2 are synthesized from glutamine, while only 30% is derived from glucose 140